Compounds > cocaine

cocaine and 3-[bis(4-fluorophenyl)methoxy]-8-methyl-8-azabicyclo[3.2.1]octane

cocaine has been researched along with 3-[bis(4-fluorophenyl)methoxy]-8-methyl-8-azabicyclo[3.2.1]octane in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's7 (87.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Allen, AC; George, C; Izenwasser, S; Katz, JL; Kline, RH; Newman, AH1
Katz, JL; Kopajtic, T; Newman, AH; Zou, MF1
Ball, WJ; Farr, CD; Norman, AB; Paula, S; Tabet, MR1
Grundt, P; Katz, JL; Kopajtic, TA; Newman, AH2
Grundt, P; Katz, JL; Kopajtic, T; Kulkarni, SS; Newman, AH1
Hansch, C; Kurup, A; Mekapati, SB; Verma, RP1
Cao, J; Desai, RI; Katz, JL; Kopajtic, T; Newman, AH; Zou, MF1

Other Studies

8 other study(ies) available for cocaine and 3-[bis(4-fluorophenyl)methoxy]-8-methyl-8-azabicyclo[3.2.1]octane

ArticleYear
Novel 4'-substituted and 4',4"-disubstituted 3 alpha-(diphenylmethoxy)tropane analogs as potent and selective dopamine uptake inhibitors.
    Journal of medicinal chemistry, 1995, Sep-29, Volume: 38, Issue:20

    Topics: Animals; Cocaine; Dopamine Uptake Inhibitors; Male; Radioligand Assay; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Tropanes

1995
Structure-activity relationship comparison of (S)-2beta-substituted 3alpha-(bis[4-fluorophenyl]methoxy)tropanes and (R)-2beta-substituted 3beta-(3,4-dichlorophenyl)tropanes at the dopamine transporter.
    Journal of medicinal chemistry, 2003, Jul-03, Volume: 46, Issue:14

    Topics: Animals; Binding, Competitive; Brain; Chlorine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Fluorine; In Vitro Techniques; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Models, Molecular; Nerve Tissue Proteins; Radioligand Assay; Rats; Stereoisomerism; Structure-Activity Relationship; Synaptosomes; Tropanes

2003
Three-dimensional quantitative structure-activity relationship modeling of cocaine binding by a novel human monoclonal antibody.
    Journal of medicinal chemistry, 2004, Jan-01, Volume: 47, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Binding, Competitive; Cocaine; Enzyme-Linked Immunosorbent Assay; Humans; Mice; Models, Molecular; Quantitative Structure-Activity Relationship; Radioligand Assay

2004
The effect of 6-substituted-4',4"-difluorobenztropines on monoamine transporters and the muscarinic M1 receptor.
    Bioorganic & medicinal chemistry letters, 2004, Jun-21, Volume: 14, Issue:12

    Topics: Benztropine; Dopamine Plasma Membrane Transport Proteins; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Protein Binding; Receptor, Muscarinic M1; Serotonin Plasma Membrane Transport Proteins; Symporters

2004
Structure-activity relationships at monoamine transporters for a series of N-substituted 3alpha-(bis[4-fluorophenyl]methoxy)tropanes: comparative molecular field analysis, synthesis, and pharmacological evaluation.
    Journal of medicinal chemistry, 2004, Jun-17, Volume: 47, Issue:13

    Topics: Animals; Brain; Carrier Proteins; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; In Vitro Techniques; Male; Membrane Glycoproteins; Membrane Transport Proteins; Models, Molecular; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Protein Binding; Quantitative Structure-Activity Relationship; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Serotonin Plasma Membrane Transport Proteins; Symporters; Tropanes

2004
The role of QSAR in dopamine interactions.
    Bioorganic & medicinal chemistry letters, 2005, Apr-15, Volume: 15, Issue:8

    Topics: Dopamine Agents; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Haloperidol; Humans; Protein Binding; Quantitative Structure-Activity Relationship; Receptors, Dopamine D2; Receptors, Dopamine D4

2005
N-8-Substituted benztropinamine analogs as selective dopamine transporter ligands.
    Bioorganic & medicinal chemistry letters, 2005, Dec-15, Volume: 15, Issue:24

    Topics: Amines; Benztropine; Binding Sites; Citalopram; Cocaine; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; Kinetics; Ligands; Models, Molecular; Molecular Conformation; Muscarinic Antagonists; Parasympatholytics; Pirenzepine

2005
Structure-activity relationship studies on a novel series of (S)-2beta-substituted 3alpha-[bis(4-fluoro- or 4-chlorophenyl)methoxy]tropane analogues for in vivo investigation.
    Journal of medicinal chemistry, 2006, Oct-19, Volume: 49, Issue:21

    Topics: Animals; Brain; Central Nervous System Stimulants; Cocaine; Discrimination Learning; Dopamine Plasma Membrane Transport Proteins; In Vitro Techniques; Male; Norepinephrine Plasma Membrane Transport Proteins; Protein Binding; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Serotonin Plasma Membrane Transport Proteins; Stereoisomerism; Structure-Activity Relationship; Tropanes

2006